Nano-sized Droplets of Self-Emulsifying System for Enhancing Oral Bioavailability of Chemotherapeutic Agent VP-16 in Rats: A Nano Lipid Carrier for BCS Class IV Drugs
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چکیده
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Self Nano Emulsifying Drug Delivery Systems for Oral Delivery of Hydrophobic Drugs
Self-emulsifying drug delivery systems (SNEDDS) are highly in quest due to their innumerable benefits like better portability, improved stability and higher drug loading, coupled with ease and economy of their production. SNEDDS are used to improve the solubility of high lipophilic drugs. SNEDDS are improving the oral bioavailability of limited water-soluble drug compounds. These SNEDDS are iso...
متن کاملSilica-Lipid Hybrid Microparticles for Improved Bioavailability of Bcs Class IV Drugs
The main objective of the current review is to cover the overview of silica lipid hybrid microparticles. Lipid-based delivery systems recognized as a potential strategy for improving the oral absorption. Clinical applications of many lipid-based formulations are limited by the lack of clear guidelines of incomplete understanding of absorption mechanism and in vitro, in vivo formulation performa...
متن کاملassessment of the effect of honey as a topical therapy for intra oral wound healing in rat.
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15 صفحه اولDevelopment and Evaluation of Solid Self Nano- Emulsifying Formulation of Rosuvastatin Calcium for Improved Bioavailability
Purpose: To develop rosuvastatin calcium-loaded self-nanoemulsifying powder for improved oral delivery of the drug. Methods: Solubility study was carried out in different oils, surfactants and co-surfactants. Based on the solubility study, liquid formulations were prepared using LAS/Capryol 90: Maisine 35-1 as oil phase and Tween 20 with Lutrol E400 as surfactant mixture (Smix). The liquid form...
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ژورنال
عنوان ژورنال: Journal of Pharmacy & Pharmaceutical Sciences
سال: 2018
ISSN: 1482-1826,1482-1826
DOI: 10.18433/jpps30097